Crizocent Crizotinib is anĀ anti-cancer medication that works by kinase inhibition and prevents the growth and metastasis of cancerous cells in the human body. Crizocent 250 mg is used for the treatment of cases who have locally advanced or metastatic non-small cell lung cancer (NSCLC). It is only used for lesions that are anaplastic lymphoma kinase (ALK)-positive or ROS 1 positive.